AOD9604 – What is it?
AOD9604 is a peptide (a chain of amino acids) which was developed and patented by a company called Metabolic Pharmaceuticals in Australia in the late 1990s. AOD stands for “Anti Obesity Drug”. This peptide has an amino acid sequence that mimics the lipolytic region of human growth hormone (the region of this hormone thought to be responsible for burning fat) and it has been promoted variously as a weight loss supplement, as an aid to muscle and cartilage repair, and a treatment for osteoarthritis by its manufacturers. It is also known as lipotropin and Tyr-hGH fragment, and is generally available these days as a transdermal cream or an injectable.
AOD9604 – Why do people use it?
AOD9604 is promoted heavily by various manufacturers as a substance that is able to burn fat and assist in the repair of muscle and cartilage. The fact that this product derives from, and claims to mimic the effects of a powerfully anabolic banned substance provides a psychological incentive to many potential users, as does the attention drawn by the AFL “peptides” scandal of early 2013 and the subsequent report by the Australian Crime Commission (1).
Whilst AOD9604 is not approved by the Australian TGA, it can be legally obtained on a doctor’s prescription and dispensed by a compounding pharmacy (2). This is true of many experimental substances, but it does big favours for the reputation of AOD9604, giving the impression that, like other drugs issued by the medical profession, it is an efficacious and high quality product. These reasons, when considered together, give a powerful impression that peptides are highly effective – they wouldn’t ban them for no reason, would they?
Metabolic Pharmaceuticals have reported that recent in vitro trials have shown that AOD9604 may stimulate the growth of bone cells, and muscle and cartilage cells. These results have not yet been reproduced in animals or humans (4). There was a lot of speculation that Metabolic was providing AOD9604 to players at the Essendon Football Club as part of a secret clinical trial, but the company has flatly denied this claim, claiming it has not run any human trials since 2007 (2). AOD9604 has been scientifically proven safe and side-effect free (2), and is apparently very difficult to detect in the blood.
A thread from one AOD9604 user:
I thought I’d report in on a trial I am currently involved in for AOD9604 as I’ve gained a lot of knowledge from you chaps and owe some back.
I’m doing endurance sports these days and trying to loose weight rather than gain it so I don’t spend much time on BB Boards.
I am currently in a trial of AOD9604 – sub q injection (not the oral – it doesn’t work).
Dosage is 300 mcg ed before bed. I’ve been going for 20 days. Had a Dexa scan at the beginning of the trial which came in at 10.4% BF (equivilant to 7.5% caliper) 103kg 195cm.
This stuff is working very well. I have not adjusted my diet and still have a choco/Ice cream binge every few nights, eat a burger here and there, have a glass of wine (mind you I average 350km/wk bike, 50km run and 7 km swim).
Caliper reading shows 2% drop. Will have dexa scan at the 40 day point and will post accurate results. Certainly looks like a significant drop so far visually.
Without going into detail, I am absolutely certain that my AOD9604 is legit.
Im not an expert on this, but ill paraphrase the basics of 9604. Its a hgh fragment that isolates the fat burning properties fo hgh without the UNWANTED side-effects of muscle growth (this might have something to do with the reason there is little interest from the BB fraternity), but the interesting point is that you can take 20x the equiv dose of AOD compared to hgh and there is no insulin resistance as it doesn’t cause igf, ext bowl, enl heart, carpal tunnel etc etc. so you can still run hgh and get the growth “sides”, but add aod for fat burning only and 10 -20 times potency.
I was going to wait for the Dexa scan to post just in case I’m “placebo’ing”, but my partner has assured me I’m not. Her words “holy shit, look at you – there are veins on you abs”
I’ll log back on when I get the 2nd scan and post results, but it’s pretty exciting.